Testicular Feminization Syndrome

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Incomplete testicular feminization syndrome.

A three and half year old girl presented to us with bilateral symmetrical swellings in the upper part of each labium majus. These were noted by her mother at birth. There was no history of any case of abnormal genitalia or inguinal hernia in her maternal aunts. Neither was there any record of intake of drugs like alcohol, hydantoins or cimetidine by the mother during pregnan On physical examina...

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Testicular Feminization Syndrome

Testicular feminization syndrome (TFS) represents a well-defined form of male pseudohermaphroditism. The patients are of female legal sex. The habitus is completely and often attractively feminine, with well-developed breasts. There is absence of axillary and pubic hair. The external genitalia are female but with a blind vagina. At laparotomy the uterus and Fallopian tubes are found to be absen...

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Androgen insensitivity syndrome (testicular feminization).

Androgen insensitivity (testicular feminization) syndrome is a rare inherited form of male pseudohermaphroditism that occurs in phenotypically normal women with adequate breast development, normal external genitalia, a vagina of variable depth, absent uterus, and sparse or absent pubic hair and axillary hair. These patients have male karyotype (XY) and negative sex chromatin. The gonad (undesce...

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Psychological aspects of the testicular feminization syndrome.

Two cases of testicular feminization are reported, in sisters. One sister was hospitalized for a polymorphous neurotic reaction; the other was apparentlyhealthy, with certain masculinoid traits in her behavior. Certain aspects of the personality structures of intersexed individuals are discussed, with special reference to the testicular feminization syndrome and to the way in which psychosexual...

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Studies on testosterone metabolism in subjects with testicular feminization syndrome.

The metabolism of radioactive testosterone simultaneously administered intravenously and either orally or percutaneously has been studied in seven patients with the syndrome of testicular feminization and compared with that of normal males and females. This investigation was carried out in order to determine the relative contribution to urinary 17-oxo and 17beta-hydroxy androstane steroids of l...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1966

ISSN: 0035-9157

DOI: 10.1177/003591576605900915